Reduced global brain metabolism but maintained vascular function in amnestic mild cognitive impairment

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منابع مشابه

Global brain hypoperfusion and oxygenation in amnestic mild cognitive impairment.

BACKGROUND To determine if global brain hypoperfusion and oxygen hypometabolism occur in patients with amnestic mild cognitive impairment (aMCI). METHODS Thirty-two aMCI and 21 normal subjects participated. Total cerebral blood flow (TCBF), cerebral metabolic rate of oxygen (CMRO2), and brain tissue volume were measured using color-coded duplex ultrasonography (CDUS), near-infrared spectrosco...

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The Role of Neuropsychological Function Tests in Predicting Amnestic Mild Cognitive Impairment in the Elderly

Background: Various studies have documented age-related changes in cognitive abilities and neural basis. Objectives: To investigate the role of neuropsychological function tests in predicting amnestic mild cognitive impairment in the elderly. Materials & Methods: In this cross-sectional study with a correlational design, the study population included elderly people over 60 years old residing ...

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Prospective memory in amnestic mild cognitive impairment.

Individuals with amnestic mild cognitive impairment (aMCI) often complain of difficulty remembering to carry out intended actions, consistent with findings of impaired prospective memory (PM) in this population. In this study, individuals with aMCI (N = 27) performed worse than healthy controls (N = 27) on the Memory for Intentions Screening Test (Raskin, 2004), including on time- and event-bas...

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Thalamic Shape and Cognitive Performance in Amnestic Mild Cognitive Impairment

OBJECTIVE This study aimed to investigate thalamic shape alterations and their relationships with various episodic memory impairments in subjects with amnestic mild cognitive impairment (aMCI). METHODS We compared volumes and morphological alterations of the thalamus between aMCI subjects and healthy controls. In addition, we investigated the correlation between thalamic deformations and vari...

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White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment.

UNLABELLED Vascular mild cognitive impairment (VaMCI) represents an early symptomatic stage of vascular cognitive impairment and might be associated to fronto-executive dysfunction. METHODS Twenty-six individuals (age: 73.11±7.90 years; 65.4% female; schooling: 9.84±3.61 years) were selected through neuropsychological assessment and neuroimaging. Clinical and neuroimaging data of VaMCI indivi...

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ژورنال

عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism

سال: 2016

ISSN: 0271-678X,1559-7016

DOI: 10.1177/0271678x16658662